NFL Week 11 odds · Tampa Bay Buccaneers (+) at San Francisco 49ers () · Chicago Bears (+10) at Detroit Lions () · New York Giants (+). NFL Week 11 odds, predictions: Picks, lines, spreads for every game ; Colts · Falcons ; Ravens -3 (Ravens favored to win by more than 3 points. Best NFL Week 11 spreads ; Cardinals vs. Texans, Texans -4, Texans ; Buccaneers vs. 49ers, 49ersnfl football odds week 11 ; Jets vs. Bills, Bills NFL Week 11 odds, spreads and schedule: Chiefs host Eagles in Super Bowl rematch · Favorites are now straight up with 5 pick'ems, favorites.
What to know for fantasy: Over the past three games, Pollard has scored a total of Against the Panthers' defense, which has given up the second-most fantasy points per game to running backs, his fortunes could change. Carolina has allowed 15 touchdowns to running backs, too. Betting nugget: Road favorites of at least seven points are ATS this season outright.
This is the second time a team has been a double-digit road favorite. In Week 3, the Cowboys lost outright as point favorites in Arizona. Matchup must-reads: Lamb, Prescott on an epic tear for Cowboys Reich takes back playcalling duties Cowboys rebound from Eagles loss with historic rout of Giants Panthers, Young 'frustrated' by loss to Bears.
Storyline to watch: This game could come down to which offensive line holds up better and protects the quarterback. Bold prediction: The Titans will score a touchdown on the road. Tennessee has scored only twice in six games away from Nissan Stadium this season, and it hasn't scored via the passing game on the road all season.
That will change against the Jaguars this week. Jacksonville's defense is giving up Stat to know: Titans running back Derrick Henry has four consecutive yard rushing games against the Jaguars. And the Jaguars have the league's fifth-best rushing defense this season, allowing just Matchup X factor: The Jaguars' offensive line.
Jacksonville ranks just 31st in pass block win rate. Injuries: Titans Jaguars. What to know for fantasy: The Titans give up the second-fewest fantasy points per game to tight ends. Tennessee has also not surrendered a touchdown to the position. Managers with Evan Engram on their rosters should have realistic expectations. Matchup must-reads: Titans must protect rookie Levis if they want him to develop Can ugly loss be a wake-up call for Jaguars, Lawrence?
Storyline to watch: Texans coach DeMeco Ryans is familiar with Cardinals quarterback Kyler Murray from his days as the 49ers defensive coordinator from to Ryans faced Murray only once in their four potential matchups due to the former No. But in their lone matchup in , Murray led the Cardinals to a win and had yards passing with a touchdown and no turnovers.
Bold prediction: Murray will pass for over yards in his second game back from right ACL surgery. Nfl football odds week 11 He will continue to build off Sunday's impressive return to the field passing yards, one rushing touchdown , taking advantage of a Texans defense that allows Stat to know: The Cardinals' eight-game losing streak on the road has them tied with the Titans for the longest active such streak in the NFL; it's their longest road losing streak since a run of nine straight from to ' He was back from injury last week, and if he can play at the level expected, based on his No.
Injuries: Cardinals Texans. What to know for fantasy: C. Stroud has completed He is going up against a Cardinals defense that gives up the eighth-most fantasy points per game to quarterbacks. Stroud leads rookie rankings Did a different Murray come back from ACL rehab. Storyline to watch: San Francisco QB Brock Purdy made his first start against the Bucs last year and now begins his second spin through the league with another game against Tampa Bay.
Both of these teams have thrived in the turnover battle, as they're tied for third in the league in turnover margin, but this game might come down to whether the Bucs can continue their defensive red zone dominance. Bold prediction: QB Baker Mayfield won't reach passing yards.
Mayfield hasn't dipped below since Week 3 against the Eagles, and that has happened only one other time this season. And while the Niners' secondary may be struggling as of late, giving up a And that's where Mayfield thrives. Stat to know: The 49ers are seeking their seventh point game this season. It would be their most through 10 games since joining the NFL in Matchup X factor: Buccaneers defensive tackle Vita Vea.
The interior of the 49ers' offensive line is fairly weak. That presents an opportunity for Vea to disrupt Purdy up the middle. If the Bucs are going to have any chance, they'll need to throw Purdy off his game. Injuries: Buccaneers 49ers. What to know for fantasy: Mayfield has posted 16 or more fantasy points in four consecutive games, but he tends to struggle against talented defenses, as shown by his 6.
Despite this, fantasy managers can place trust in Rachaad White in their lineups. The 49ers' defense ranks among the top 10 in the league in targets and receptions allowed to running backs per game. Matchup must-reads: Mayfield thumb OK to face 49ers Purdy after 17 NFL starts Bucs look to take momentum into 49ers game. Storyline to watch: Joe Brady's first game as interim offensive coordinator will come with quite the challenge going against a Jets defense that held Buffalo to 16 points in Week 1 and forced three QB Josh Allen interceptions and a fumble.
How the Bills' offense looks under Brady and going against a defense that allows the third-fewest yards per play in the league 4. Bold prediction: Rookie RB Israel Abanikanda , who will be active for the first time, will end the Jets' touchdown drought with a long run. His sub The Jets have gone two straight games without a touchdown, one shy of the franchise record and Buffalo has failed to win the turnover battle in six straight games, its longest such streak since the Bills haven't gone seven straight without winning the turnover battle since Denver showed last week that shutting down receiver Stefon Diggs can be an effective strategy against the Bills, who lack a super threatening No.
In Gardner and Reed, the Jets have the corners to do it. Injuries: Jets Bills. What to know for fantasy: While the Jets' secondary is formidable, New York has allowed the second-most rushing yards per game. The Bills' offensive line ranks second in run block win rate. So don't hesitate to get James Cook into your lineups. Also, feel confident in starting tight end Dalton Kincaid , who may be relied upon heavily against the Jets due to their stout secondary.
Matchup must-reads: Saleh: If Rodgers says he wants to play, he'll play Brady's to-do list starts with restoring Allen's confidence How the Jets' offense got stuck in neutral Allen says Dorsey would have job if Bills played better. Storyline to watch: Quarterback Matthew Stafford is expected to play Sunday after injuring his right thumb against the Cowboys in Week 8. The Rams' offense managed just yards in their loss to the Packers without Stafford and the team has lost three in a row.
Stafford will face a Seahawks defense that is allowing Bold prediction: Boye Mafe will welcome Stafford back from his injury by sacking him at least two times. The Seahawks' second-year outside linebacker has a sack in a franchise-record seven consecutive games. Since stats became an official statistic in , only 11 players have recorded a sack in eight straight games in the same season.
Mafe, who ranks fourth among edge players in pass rush win rate, will join that company Sunday. The Rams have given up 21 sacks this season. Stat to know: Puka Nacua has receiving yards this season. He needs 43 yards to pass Cooper Kupp for the second most by a Rams rookie in franchise history. Matchup X factor: Seahawks cornerback Devon Witherspoon.
He plays mostly in the slot these days, and that means frequent matchups with Kupp. When Stafford is healthy, the Rams' offense can be feisty, so Seattle's defense will need to show up. Injuries: Seahawks Rams. What to know for fantasy: The Seahawks' defense has allowed the most rushing yards per game This season, Seattle has allowed the fifth-most fantasy points per game to running backs.
For Darrell Henderson Jr. Betting nugget: The Rams have covered six straight meetings, including playoffs. Matchup must-reads: Mafe making impressive second-year jump Stafford feels confident ahead of return from injury Four biggest issues the Rams must grapple with. Storyline to watch: It's about who keeps the momentum.
Joshua Dobbs has been a lifeguard for the Vikings at quarterback since Kirk Cousins ' season-ending injury torn right Achilles. Chargers cowboys over under Six of their last seven games have gone under the total. New York Jets Buffalo Bills The Jets have covered three straight meetings including two outright wins as an underdog. The last four meetings have gone under the total. The Rams have covered six straight meetings including playoffs.
The Vikings have covered five straight games, the longest active streak in the NFL. They are ATS when laying more than a point at home with Wilson. Home favorites are ATS in prime-time games in the last five seasons. Philadelphia Eagles Kansas City Chiefs Skip to main content Skip to navigation. NFL Week 11 games lines: Chiefs 2. Boston Celtics. NHL odds to win playoffs, Stanley Cup, conference futures.
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Buy them here. Get all-access to exclusive stories. Subscribe to The Athletic for in-depth coverage of your favorite players, teams, leagues and clubs. Nfl football odds week 11 Try a week on us. Andrew DeWitt is The Athletic's senior editor for sports betting. Joseph News-Press. He graduated from the University of Missouri and is from Kansas City.